My previous ideas were:
1. Staffroom Chaos:
A woman appears to be monologuing to herself with exaggerated gestures in a staffroom until the camera reveals she is not alone. The school they are in has been ravaged and smashed to pieces, giving the two teachers the reason to be in the states they are.
2. Team Carrying:
A skinny jock is doing laps of a track, but his girlfriend is this huge woman and has demanded that instead of her having to run she will sit on his shoulders. The jock is a tiny little stick compared to the girl so disobeying the laws of physic's should make this really ridiculous to watch.
3. Playing make belief:
Two kids are in a playground playing make believe whilst this audio clip plays, they have put on parts of the teachers clothing, near the end of the animation you can see the two teachers have been wrapped up in toilet paper, strapped to a bar on the jungle gym.
4. Team Carrying, Role Reversal:
Instead of the girl being the on the top, this time, it is the guy. This guy is like a fat small child and the girl is a small 6th grader. They are still doing laps of a track but the designs have significantly changed.
Now taking previous ideas, combining Alan and Justin's Feedback I have come up with 'Toddler Takeover'. This animation begins with a female teacher tied up and complaining. in the background you can see other teachers tied up and gagged with either tape or toys. The kids have broken into the staff schoolroom and decided to take it for themselves. The animation finishes with a 4-year-old opening the staff fridge, grabbing a beer can and downing the sucker.
There are certain aspects to take into account with this animation, the way it is first shown is with two teachers completely out of breath tied up. What appears to be next to them is a wall but is really a fridge, that is how the baby says "I need a beer". The whole start is meant to be sinister, having a red hand print on the wall, assumed to be blood but is really a child's hand painting, the lighting making the baby look massive, then by the end the big reveal is that it is just some silly kids.
The animation's theme is based on something that is assumed to be sinister, then revealed to be silly.
The only issue with this idea is it might be slightly difficult to incorporate the sound well into the animation, however with enough refinement this should work quite nicely.